Research Scientist

Responsibilities will include: Preparing DNA and RNA sequencing libraries using established and novel chemistries. Developing, optimising and troubleshooting molecular biology protocols, including nanopore sequencing workflows. Planning and independently delivering research projects from experimental design through to data generation and evaluation within an agile research environment. Performing preliminary data analysis and visualisation using appropriate bioinformatics tools. Maintaining clear experimental records and producing high-quality protocols, technical reports and project updates. Collaborating effectively with multiple teams across Oxford Nanopore. Providing technical guidance and mentorship to junior colleagues and interns. Staying up to date with developments in sequencing technology, molecular biology and RNA research. What We’re Looking For... Essential skills and experience: PhD , or equivalent research experience, in RNA biology, molecular biology, biochemistry, chemical biology or a related discipline. Proven background in RNA molecular biology, including RNA purification, enzymatic manipulation and integrity assessment. Strong understanding of RNA stability, degradation, secondary structure and enzymology. Demonstrated ability to independently design, optimise and troubleshoot complex experiments. Familiarity or willingness to develop proficiency in Python, Bash or command-line bioinformatics tools. Desirable skills and experience: Experience with long-read transcriptomics, ideally Oxford Nanopore direct-RNA sequencing. Experience working with synthetic, chemically modified or therapeutic RNA molecules, including an understanding of RNA modification and end chemistry. Experience developing RNA manipulation, capture or library-preparation methods, and/or studying RNA structure or interactions. Familiarity with computational tools for bioinformatics analyses and data visualization. Knowledge of functional genomics, including nucleotide modifications and genome regulation.